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Cayman Chk2 Inhibitor Ii; Purity- Greater Than Or Equal To 98%; S
List Price
$120.00
Your Price
$120.00
Cayman Chk2 Inhibitor Ii; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17552-10
MFG.PART:
17552-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Chk2 inhibitor II is a selective, ATP-competitive inhibitor of the DNA damage control kinase, checkpoint kinase 2 (IC50 = 15 nM).1 It has been shown to prevent apoptosis in human T-cells exposed to ionizing radiation (EC50 = 3-7.6 µM).1 This compound has been used to target the role of Chk2 in cellular signaling in response to DNA damage.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[4-(4-chlorophenoxy)phenyl]-1H-benzimidazole-6-carboxamide
CAS Number
516480-79-8
Synonyms
- BML-277
- C 3742
- Checkpoint Kinase 2 Inhibitor II
Molecular Formula
C20H14ClN3O2
Formula Weight
363.8
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 20 mg/ml
- DMSO: 20 mg/ml
- DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml
- Ethanol: 10 mg/ml
λmax
282, 256, 314 nm
SMILES
NC(C1=CC=C2C(NC(C3=CC=C(OC4=CC=C(Cl)C=C4)C=C3)=N2)=C1)=O
InChi Code
InChI=1S/C20H14ClN3O2/c21-14-4-8-16(9-5-14)26-15-6-1-12(2-7-15)20-23-17-10-3-13(19(22)25)11-18(17)24-20/h1-11H,(H2,22,25)(H,23,24)
InChi Key
UXGJAOIJSROTTN-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17552-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 17552-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 516480-79-8 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |