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Cayman Mjn110; Purity- Greater Than Or Equal To 95%; Size- 10 Mg
List Price
$155.00
Your Price
$155.00
Cayman Mjn110; Purity- Greater Than Or Equal To 95%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17583-10
MFG.PART:
17583-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
ALK-IN-1 is an analog of AP26113, a phosphine oxide-containing ALK inhibitor. ALK-IN-1 potently inhibits ALK (IC50 = 0.07 nM) over IGF-1R and InsR (IC50s = 3.2 and 100 nM, respectively). It drives cell death in (ALK+) Karpas-299 lymphoma cells with an IC50 value of 41.5 nM, while killing (ALK-) U937 cells with an IC50 value of 1,718 nM.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-chloro-N2 -[4-[4-(dimethylamino)- 1-piperidinyl]- 2-methoxyphenyl]- N4-[2-(dimethylphosphinyl) phenyl]- 2,4-pyrimidinediamine
CAS Number
1197958-12-5
Molecular Formula
C26H34ClN6O2P
Formula Weight
529.0
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 25 mg/ml
- Ethanol: 25 mg/ml
- PBS (pH 7.2): 0.3 mg/ml
λmax
288 nm
SMILES
CN(C)C1CCN(C2=CC(OC)=C(NC3=NC=C(Cl)C(NC4=CC=CC=C4P(C)(C)=O)=N3)C=C2)CC1
InChi Code
InChI=1S/C26H34ClN6O2P/c1-32(2)18-12-14-33(15-13-18)19-10-11-21(23(16-19)35-3)30-26-28-17-20(27)25(31-26)29-22-8-6-7-9-24(22)36(4,5)34/h6-11,16-18H,12-15H2,1-5H3,(H2,28,29,30,31)
InChi Key
OVDSPTSBIQCAIN-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17583-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 17583-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1438416-21-7 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |