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Cayman Ve-821; Purity- Greater Than Or Equal To 98%; Size- 10 Mg
List Price
$177.45
Your Price
$177.45
Cayman Ve-821; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17587-10
MFG.PART:
17587-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
ARN14988 is a potent inhibitor of acid ceramidase (IC50 = 12.8 nM for the human enzyme). It inhibits acid ceramidase activity and increases levels of C16 dihydro ceramide (Item No. ) and C16 ceramide (Item No. ) in A375, G361, M14, MeWo, MNT-1, and SK-MEL-28 melanoma cells. ARN14988 also reduces growth of A375 and G361 melanoma cells (EC50s = 41.8 and 67.7 µM, respectively).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-chloro-3- [(hexylamino) carbonyl]-3,6- dihydro-2,6- dioxo-1(2H)- pyrimidine carboxylic acid, 2-methyl propyl ester
CAS Number
1502027-70-4
Molecular Formula
C16H24ClN3O5
Formula Weight
373.8
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml
- Ethanol: slightly soluble
λmax
216, 269 nm
SMILES
O=C(OCC(C)C)N(C(C(Cl)=CN1C(NCCCCCC)=O)=O)C1=O
InChi Code
InChI=1S/C16H24ClN3O5/c1-4-5-6-7-8-18-14(22)19-9-12(17)13(21)20(15(19)23)16(24)25-10-11(2)3/h9,11H,4-8,10H2,1-3H3,(H,18,22)
InChi Key
PBVLSEVDIRSYGE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17587-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 17587-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1232410-49-9 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |