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Cayman Ve-821; Purity- Greater Than Or Equal To 98%; Size- 5 Mg;
List Price
$121.80
Your Price
$121.80
Cayman Ve-821; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17587-5
MFG.PART:
17587-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
AZD 2932 is an inhibitor of VEGFR2, PDGFRβ, CSF1R, c-KIT, and FLT3 receptor tyrosine kinases (IC50s = 4, 8, 100, 9, and 7 nM, respectively). It also inhibits Pdgfrα phosphorylation (IC50 = 2 nM) in lysates from C6 rat glial tumors grown in athymic mice. AZD 2932 (12.5-50 mg/kg) reduces tumor growth and inhibits Pdgfrβ and Vegfr2 phosphorylation in a 1:1 ratio in a C6 mouse xenograft model. Xenograft models using non-PDGFR expressing tumor cells were insensitive to AZD 2932 treatment.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[(6,7-
CAS Number
883986-34-3
Molecular Formula
C24H25N5O4
Formula Weight
447.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 0.25 mg/ml
- DMSO: 0.25 mg/ml
λmax
239, 320 nm
SMILES
COC1=CC2=C(C(OC3=CC=C(CC(NC4=CN(C(C)C)N=C4)=O)C=C3)=NC=N2)C=C1OC
InChi Code
InChI=1S/C24H25N5O4/c1-15(2)29-13-17(12-27-29)28-23(30)9-16-5-7-18(8-6-16)33-24-19-10-21(31-3)22(32-4)11-20(19)25-14-26-24/h5-8,10-15H,9H2,1-4H3,(H,28,30)
InChi Key
TWYCZJMOEMMCGC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17587-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 17587-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1232410-49-9 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |