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Cayman Meosuc-Aapv-Pna; Purity- Greater Than Or Equal To 98%; Siz
List Price
$163.00
Your Price
$163.00
Cayman Meosuc-Aapv-Pna; Purity- Greater Than Or Equal To 98%; Size- 50 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17601-50
MFG.PART:
17601-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides.1 Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to destroy pathogens.2 Evaluating these enzymes is helpful to understanding inflammatory autoimmune processes. MeOSuc-AAPV-pNA is a highly sensitive peptide substrate that is hydrolyzed by both human and mouse neutrophil elastase and PR3, but not cathepsin G or chymotrypsin.3,4 Enzyme activity can be quantified by colorimetric detection of free p-nitroanilide at 405 nm.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-L-valinamide
CAS Number
70967-90-7
Molecular Formula
C27H38N6O9
Formula Weight
590.6
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 5 mg/ml
- PBS (pH 7.2): Slightly soluble
λmax
210, 224, 315 nm
SMILES
COC(CCC(N[C@@H](C)C(N[C@@H](C)C(N1CCC[C@H]1C(N[C@H](C(NC2=CC=C([N+]([O-])=O)C=C2)=O)C(C)C)=O)=O)=O)=O)=O
InChi Code
InChI=1S/C27H38N6O9/c1-15(2)23(26(38)30-18-8-10-19(11-9-18)33(40)41)31-25(37)20-7-6-14-32(20)27(39)17(4)29-24(36)16(3)28-21(34)12-13-22(35)42-5/h8-11,15-17,20,23H,6-7,12-14H2,1-5H3,(H,28,34)(H,29,36)(H,30,38)(H,31,37)/t16-,17-,20-,23-/m0/s1
InChi Key
VLVGCNNWNUERRZ-OSAZLGQLSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17601-50 |
|---|---|
| Featured | No |
| Supplier Part Number | 17601-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 70967-90-7 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |