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Cayman Tsi-01; Purity- Greater Than Or Equal To 95%; Size- 5 Mg;
List Price
$216.00
Your Price
$216.00
Cayman Tsi-01; Purity- Greater Than Or Equal To 95%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17628-5
MFG.PART:
17628-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase that promotes cell proliferation and blocks apoptosis. CH5424802 is an ATP-competitive inhibitor of ALK (IC50 = 1.9 nM) that also inhibits F1174L, R1275Q, and L1196M mutants of ALK (IC50s = 1.0, 3.5, and 1.6 nM, respectively)., It shows more than 500-fold selectivity for ALK over a panel of 24 other kinases. CH5424802 is orally available and inhibits the growth of tumors in mouse xenograft models of nonsmall cell lung cancer and anaplastic large-cell lymphoma.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
9-
CAS Number
1256580-46-7
Synonyms
- Alectinib
- RO5424802
Molecular Formula
C30H34N4O2
Formula Weight
482.6
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 3 mg/mL
- DMF:PBS(pH7.2) (1:2): 0.3 mg/mL
λmax
232, 262, 281, 337 nm
SMILES
CCC1=CC2=C(C(C)(C)C(NC3=C4C=CC(C#N)=C3)=C4C2=O)C=C1N(CC5)CCC5N6CCOCC6
InChi Code
InChI=1S/C30H34N4O2/c1-4-20-16-23-24(17-26(20)34-9-7-21(8-10-34)33-11-13-36-14-12-33)30(2,3)29-27(28(23)35)22-6-5-19(18-31)15-25(22)32-29/h5-6,15-17,21,32H,4,7-14H2,1-3H3
InChi Key
KDGFLJKFZUIJMX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17628-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 17628-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 704878-75-1 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |