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Cayman Mn-64; Purity- Greater Than Or Equal To 98%; Size- 5 Mg
List Price
$93.00
Your Price
$93.00
Cayman Mn-64; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17635-5
MFG.PART:
17635-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
LOXO-101 is an inhibitor of the tropomyosin-related kinases TrkA, TrkB, and TrkC (IC50s = 2-20 nM). It is selective for TrkA, -B, and -C over a panel of 226 kinases at 1 μM. LOXO-101 inhibits the growth of CUTO-3.29, KM12, and MO-91 patient-derived cancer cell lines (IC50s = <100, <10, and <10 nM, respectively). In vivo, LOXO-101 (60 and 200 mg/kg) reduces tumor growth in a KM12 mouse xenograft model.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3S)-N-[5-[(2R)-
CAS Number
1223403-58-4
Synonyms
- ARRY-470
- Larotrectinib
Molecular Formula
C21H22F2N6O2
Formula Weight
428.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMSO: 4 mg/ml
λmax
264 nm
SMILES
O=C(N1CC[C@H](O)C1)NC2=C3N(N=C2)C=CC(N4CCC[C@@H]4C5=C(F)C=CC(F)=C5)=N3
InChi Code
InChI=1S/C21H22F2N6O2/c22-13-3-4-16(23)15(10-13)18-2-1-7-28(18)19-6-9-29-20(26-19)17(11-24-29)25-21(31)27-8-5-14(30)12-27/h3-4,6,9-11,14,18,30H,1-2,5,7-8,12H2,(H,25,31)/t14-,18+/m0/s1
InChi Key
NYNZQNWKBKUAII-KBXCAEBGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17635-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 17635-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 92831-11-3 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |