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Cayman Cym 5520; Purity- Greater Than Or Equal To 95%; Size- 1 Mg
List Price
$32.00
Your Price
$32.00
Cayman Cym 5520; Purity- Greater Than Or Equal To 95%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17638-1
MFG.PART:
17638-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
NDT 9513727 is a competitive antagonist of the C5a receptor (C5aR; IC50 = 11.6 nM for human recombinant receptors) that has inverse agonist activity in a GTPγ[35S] assay., It is selective for human recombinant over rat and mouse recombinant C5aRs (IC50 = >10 µM for both) but does have activity at macaque and gerbil receptors (IC50s = 7.3 and 6.4 nM, respectively). NDT 9513727 inhibits degranulation in U937 cells stimulated with C5a (IC50 = 7.1 nM). It also prevents neutropenia induced by human recombinant C5a in gerbils (ED50 = 2.2 mg/kg) and in cynomolgus macaques when administered at doses of 5 and 25 mg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N,N-bis(1,3-
CAS Number
439571-48-9
Molecular Formula
C36H35N3O4
Formula Weight
573.7
Purity
≥98%
Formulation
A solid
Solubility
- DMSO: 100 mM
- Ethanol: 100 mM
SMILES
CCCCN1C(CN(CC2=CC=C3C(OCO3)=C2)CC4=CC=C5C(OCO5)=C4)=C(C6=CC=CC=C6)N=C1C7=CC=CC=C7
InChi Code
InChI=1S/C36H35N3O4/c1-2-3-18-39-30(35(28-10-6-4-7-11-28)37-36(39)29-12-8-5-9-13-29)23-38(21-26-14-16-31-33(19-26)42-24-40-31)22-27-15-17-32-34(20-27)43-25-41-32/h4-17,19-20H,2-3,18,21-25H2,1H3
InChi Key
ITACCRHKSPSKKL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17638-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 17638-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 1449747-00-5 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |