Cayman Pd 174265; Purity- Greater Than Or Equal To 98%; Size- 5 M

Bacterial DNA gyrase is a heterodimeric type II topoisomerase that negatively supercoils circular double-stranded DNA.^, Oxolinic acid is a quinolone antibiotic that inhibits bacterial DNA gyrase, but not eukaryotic topoisomerases, reversibly binding gyrase subunit A in gyrase-DNA complexes, blocking supercoiling activity and inhibiting DNA synthesis at 0.5-5 µg/ml.^,, Oxolinic acid also blocks neuronal uptake of dopamine in mammals (IC₅₀ = 4.3 µM), leading to an increase in locomotor activity.

WARNING This product is not for human or veterinary use.