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Cayman Amylose; Size- 5 G
List Price
$396.00
Your Price
$396.00
Cayman Amylose; Size- 5 G; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17664-5
MFG.PART:
17664-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
TBPB is an allosteric agonist of M1 muscarinic acetylcholine receptors (mAChRs; EC50 = 158 nM in CHO-K1 cells expressing rat recombinant receptors). It is selective for M1 over M2-5 receptors at concentrations up to 10 μM. TBPB (3 μM) potentiates NMDA-evoked currents in CA1 pyramidal cells. It increases production of the non-amyloidogenic amyloid precursor protein (APP) cleavage products APPsα and CTFα in PC12 cells overexpressing the human M1 receptor and APP when used at a concentration of 1 μM. TBPB decreases amphetamine-induced hyperlocomotion in a rat model that is predictive of antipsychotic-like activity.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1,3-dihydro-
CAS Number
634616-95-8
Molecular Formula
C25H32N4O
Formula Weight
404.6
Purity
≥98%
Formulation
A crystalline solid
Solubility
- Chloroform: 30 mg/ml
- DMF: 10 mg/ml
- DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml
SMILES
CC(C=CC=C1)=C1CN(CC2)CCC2N3CCC(N4C(NC5=C4C=CC=C5)=O)CC3
InChi Code
InChI=1S/C25H32N4O/c1-19-6-2-3-7-20(19)18-27-14-10-21(11-15-27)28-16-12-22(13-17-28)29-24-9-5-4-8-23(24)26-25(29)30/h2-9,21-22H,10-18H2,1H3,(H,26,30)
InChi Key
CWPKTBMRVATCBL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17664-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 17664-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United Kingdom |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 9005-82-7 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |