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Cayman Nvp-Tae226; Purity- Greater Than Or Equal To 98%; Size- 1
List Price
$44.00
Your Price
$44.00
Cayman Nvp-Tae226; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17685-1
MFG.PART:
17685-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
NVP-TAE226 is an inhibitor of focal adhesion kinase (FAK; IC50 = 5.5 nM) and the related proline-rich tyrosine kinase 2-β (PYK2β; IC50 = 5 nM). It can also inhibit the insulin-like growth factor 1 receptor (IC50 = 0.16 µM) as well as the activity of its downstream target genes such as MAPK and Akt. NVP-TAE226 has been shown to inhibit glioma and ovarian tumor growth in in vivo tumor models.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[[5-chloro-
CAS Number
761437-28-9
Synonyms
- TAE226
Molecular Formula
C23H25ClN6O3
Formula Weight
468.9
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml
- DMSO: 10 mg/ml
λmax
285 nm
SMILES
COC1=CC(N2CCOCC2)=CC=C1NC3=NC=C(Cl)C(NC4=CC=CC=C4C(NC)=O)=N3
InChi Code
InChI=1S/C23H25ClN6O3/c1-25-22(31)16-5-3-4-6-18(16)27-21-17(24)14-26-23(29-21)28-19-8-7-15(13-20(19)32-2)30-9-11-33-12-10-30/h3-8,13-14H,9-12H2,1-2H3,(H,25,31)(H2,26,27,28,29)
InChi Key
UYJNQQDJUOUFQJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17685-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 17685-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 761437-28-9 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |