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Cayman Lh 846; Purity- Greater Than Or Equal To 98%; Size- 1 Mg;
List Price
$32.00
Your Price
$32.00
Cayman Lh 846; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17686-1
MFG.PART:
17686-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
LH 846 is a benzothiazole analog that selectively inhibits casein kinase (CK) 1δ (IC50 = 290 nM). It inhibits CK1ε and CK1α at much higher concentrations (IC50s = 1.3 and 2.5 μM, respectively) but does not inhibit CK2. LH 846 has been shown to inhibit CK1δ-dependent phosphorylation and degradation of PER1 protein and to lengthen the circadian period in U2OS cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(5-chloro-
CAS Number
639052-78-1
Molecular Formula
C16H13ClN2OS
Formula Weight
316.8
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 5 mg/mL
- DMSO: 5 mg/mL
λmax
212, 233, 274, 296, 307 nm
SMILES
CC1=C(Cl)C=C(N=C(NC(CC2=CC=CC=C2)=O)S3)C3=C1
InChi Code
InChI=1S/C16H13ClN2OS/c1-10-7-14-13(9-12(10)17)18-16(21-14)19-15(20)8-11-5-3-2-4-6-11/h2-7,9H,8H2,1H3,(H,18,19,20)
InChi Key
DYHAMRNAHTWYKY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17686-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 17686-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 639052-78-1 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |