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Cayman 6-OAU
List Price
$103.00
Your Price
$103.00
Cayman 6-OAU - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17687-1
MFG.PART:
17687-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
GPR84 is a Gαi protein-coupled receptor that is activated by medium-chain free fatty acids, but only at micromolar concentrations. GPR84 is expressed in leukocytes and its expression is further induced by LPS., 6-OAU is a synthetic agonist for GPR84 (EC50 = 512 nM). It has insignificant actions at a panel of 69 other receptors, channels, or transporters. 6-OAU promotes chemotaxis in human neutrophils (EC50 = 318 nM) and amplifies TNF-α production by LPS-treated U937 macrophages. In rats, 6-OAU (1 mg/mL) drives the recruitment of neutrophils and macrophages when injected into a subcutaneous air pouch and raises serum levels of CXCL1 (growth-regulated α protein) when delivered intravenously.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
6-(octylamino)-2,4(1H,3H)-pyrimidinedione
CAS Number
83797-69-7
Molecular Formula
C12H21N3O2
Formula Weight
239.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 0.25 mg/mL
- DMSO: 0.25 mg/mL
λmax
265 nm
SMILES
O=C1NC(NCCCCCCCC)=CC(N1)=O
InChi Code
InChI=1S/C12H21N3O2/c1-2-3-4-5-6-7-8-13-10-9-11(16)15-12(17)14-10/h9H,2-8H2,1H3,(H3,13,14,15,16,17)
InChi Key
PFSWASUQURIOOR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17687-1 |
|---|---|
| Supplier Part Number | 17687-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 83797-69-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |