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Cayman Clemizole (hydrochloride)
List Price
$454.00
Your Price
$454.00
Cayman Clemizole (hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17695-50
MFG.PART:
17695-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Clemizole is an antihistamine that antagonizes the histamine 1 receptor at high nanomolar concentrations.1,2 It less potently blocks transient receptor potential canonical channel 5 (TRPC5; IC50 = 1.0-1.3 µM), with at least 6-fold selectivity for TRPC5 over other TRP channels.3 Clemizole also has hepatitis C antiviral action through inhibition of NS4B function, showing synergy with boceprevir (Item No. 18379), and it inhibits seizures in a zebrafish model of Dravet Syndrome.4,5
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-[(4-chlorophenyl)methyl]-
CAS Number
1163-36-6
Synonyms
- Al 20
- Allercur
Molecular Formula
C19H20ClN3 • HCl
Formula Weight
362.3
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 5 mg/mL
- DMSO: 10 mg/mL
- DMSO:PBS(pH 7.2) (1:2): 0.3 mg/mL
- Ethanol: 2 mg/mL
λmax
205, 252, 276, 283 nm
SMILES
ClC(C=C1)=CC=C1CN2C(CN3CCCC3)=NC4=CC=CC=C42.Cl
InChi Code
InChI=1S/C19H20ClN3.ClH/c20-16-9-7-15(8-10-16)13-23-18-6-2-1-5-17(18)21-19(23)14-22-11-3-4-12-22;/h1-2,5-10H,3-4,11-14H2;1H
InChi Key
DNFMJYXRIMLMBZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17695-50 |
|---|---|
| Supplier Part Number | 17695-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 1163-36-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |