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Cayman Fk-3311; Purity- Greater Than Or Equal To 98%; Size- 10 Mg
List Price
$214.00
Your Price
$214.00
Cayman Fk-3311; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17697-10
MFG.PART:
17697-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
D-NMAPPD is an inhibitor of ceramidase. It induces cell death in SW403 colon adenocarcinoma cells in a time- and concentration-dependent manner but has no effect on viability of rat hepatocytes, Kupffer cells, or sinusoidal endothelial cells when used at a concentration of 100 mM. D-NMAPPD increases intracellular ceramide accumulation and cytochrome C release and induces apoptosis in SW403 cells, effects that can be prevented by the caspase-3 inhibitor Ac-DEVD-CHO (Item No. ). In vivo, D-NMAPPD (75 mg/kg) reduces tumor growth and the number of hepatic metastases in SW403 and LoVo colon cancer mouse xenograft models.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-
CAS Number
35922-06-6
Synonyms
- (1R,2R)-
B13 - CAY10466
Molecular Formula
C23H38N2O5
Formula Weight
422.6
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 10 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 20 mg/ml
- Ethanol:PBS (pH 7.2)(1:2): .3 mg/ml
λmax
202, 275 nm
SMILES
OC[C@@H](N([H])C(CCCCCCCCCCCCC)=O)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1
InChi Code
InChI=1S/C23H38N2O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-22(27)24-21(18-26)23(28)19-14-16-20(17-15-19)25(29)30/h14-17,21,23,26,28H,2-13,18H2,1H3,(H,24,27)/t21-,23-/m1/s1
InChi Key
XUSDVLHKNBOGJY-FYYLOGMGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17697-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 17697-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 116686-15-8 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |