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Cayman CE3F4
List Price $676.00 Your Price $676.00
Cayman CE3F4 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-17767-50
MFG.PART: 17767-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Exchange protein activated by cAMP (Epac) proteins mediate cAMP signaling independent of protein kinase A (PKA). CE3F4 is an uncompetitive inhibitor of Epac1 activity toward its effector Rap1 in vitro (IC50 = 23 µM) and in cells.1,2. It has no effect on PKA activity. CE3F4 blocks Epac1-induced autophagy in cardiomyocytes stimulated with isoprenaline and blocks the activation of transient receptor potential canonical (TRPC) channels by the Epac activator 8-pCPT.3,4
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5,7-
CAS Number
143703-25-7
Molecular Formula
C11H10Br2FNO
Formula Weight
351.0
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS (pH 7.2) (1:10): 0.09 mg/mL
- Ethanol: 5 mg/mL
λmax
220, 294 nm
SMILES
O=C([H])N1C(C)CCC2=C(Br)C(F)=C(Br)C=C21
InChi Code
InChI=1S/C11H10Br2FNO/c1-6-2-3-7-9(15(6)5-16)4-8(12)11(14)10(7)13/h4-6H,2-3H2,1H3
InChi Key
ZZLQPWXVZCPUGC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17767-50 |
|---|---|
| Supplier Part Number | 17767-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 143703-25-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |