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Cayman Balicatib
List Price $168.00 Your Price $168.00
Cayman Balicatib - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-17995-10
MFG.PART: 17995-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Balicatib is a potent inhibitor of cathepsin K (IC50s = 1.4, 56, and 480 nM for human, rat, and mouse forms, respectively)., it is at least 100-fold selective for cathepsin K over cathepsins B, L, and S. Balicatib has a basic lipophilic nature, resulting in lysosomal trapping and increased selectivity for lysosomal cathepsin K.,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[1-[[(cyano
CAS Number
354813-19-7
Synonyms
- AAE581
Molecular Formula
C23H33N5O2
Formula Weight
411.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/mL
- DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL
- DMSO: 10 mg/mL
- Ethanol: 0.5 mg/mL
λmax
202, 297 nm
SMILES
CCCN1CCN(C2=CC=C(C(NC3(C(NCC#N)=O)CCCCC3)=O)C=C2)CC1
InChi Code
InChI=1S/C23H33N5O2/c1-2-14-27-15-17-28(18-16-27)20-8-6-19(7-9-20)21(29)26-23(10-4-3-5-11-23)22(30)25-13-12-24/h6-9H,2-5,10-11,13-18H2,1H3,(H,25,30)(H,26,29)
InChi Key
LLCRBOWRJOUJAE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17995-10 |
|---|---|
| Supplier Part Number | 17995-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 354813-19-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |