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Cayman DY 131
List Price $68.00 Your Price $68.00
Cayman DY 131 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-17999-5
MFG.PART: 17999-5
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
The estrogen-related receptors (ERRs) are orphan nuclear receptors with homology to the ER family and are expressed in tissues with high metabolic demand. DY 131 is a selective agonist of the ERRβ/γ receptor (EC50 = 130 nM).1,2 It does not affect the ERRα receptor nor the ERs α and β at concentrations up to 30 µM.1,2 DY 131 has been used to potentiate ERRγ-induced growth inhibition in LNCaP and DU145 prostate cancer cell lines in order to demonstrate an antiproliferative/tumor-suppressing function for ERRγ in prostate cancer.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-hydroxy-benzoic acid 2-[[4-(diethylamino)phenyl]methylene]hydrazide
CAS Number
95167-41-2
Synonyms
- GSK9089
Molecular Formula
C18H21N3O2
Formula Weight
311.4
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 2 mg/mL
- DMSO: 3 mg/mL
- DMSO:PBS(pH7.2) (1:1): 0.5 mg/mL
λmax
247, 363 nm
SMILES
OC1=CC=C(C(N/N=C/C2=CC=C(N(CC)CC)C=C2)=O)C=C1
InChi Code
InChI=1S/C18H21N3O2/c1-3-21(4-2)16-9-5-14(6-10-16)13-19-20-18(23)15-7-11-17(22)12-8-15/h5-13,22H,3-4H2,1-2H3,(H,20,23)/b19-13+
InChi Key
WLKOCYWYAWBGKY-CPNJWEJPSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17999-5 |
|---|---|
| Supplier Part Number | 17999-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 95167-41-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |