Cayman Micafungin (Sodium Salt); Purity- Greater Than Or Equal To

Etofenamate-d₄ is intended for use as an internal standard for the quantification of etofenamate (Item No. ) by GC- or LC-MS. Etofenamate is a non-steroidal anti-inflammatory drug (NSAID) and diethylene glycol ester form of flufenamic acid (Item No. ) that has anti-inflammatory and analgesic activities.^, It inhibits lipoxygenase isolated from guinea pig leukocytes (IC₅₀ = 5.3 μM) and the production of prostaglandin E₂ (PGE₂; Item No. ) in stimulated rat peritoneal macrophages. In vivo, etofenamate reduces acetic acid-induced vascular permeability in mice and UV-induced erythema in guinea pigs in a dose-dependent manner at doses ranging from 40-320 and 5-20 mg/kg, respectively. Etofenamate (40 mg/kg per day for 21 days) inhibits inflammation in a rat model of adjuvant-induced arthritis. It also decreases the pain response in a silver nitrate-induced rat model of arthritis and the acetic acid-induced writhing test in mice, indicating analgesic activity. Formulations containing etofenamate have been used in the treatment of osteoarthritis.

WARNING This product is not for human or veterinary use.