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Cayman Scr7; Purity- Greater Than Or Equal To 95%; Size- 5 Mg
List Price
$109.00
Your Price
$109.00
Cayman Scr7; Purity- Greater Than Or Equal To 95%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18015-5
MFG.PART:
18015-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
m-Iodobenzylguanidine (MIBG) is an analogue of norepinephrine with anticancer activity. It inhibits cell growth in a panel of human and mouse leukemia, fibrosarcoma, melanoma, and neuroblastoma cell lines when used at a concentration of 20 µg/ml and reduces clonogenic survival of L1210 leukemia cells in a concentration-dependent manner. MIBG increases survival in N1E155 and L1210 mouse xenograft models when administered at doses of 40 and 20 mg/kg, respectively. It selectively accumulates in chromaffin tissues and tumors and formulations containing radiolabeled forms of MIBG have been used as imaging agents in the diagnosis and treatment of neuroendocrine tumors. MIBG also inhibits ADP-ribose linkage to membrane proteins in turkey erythrocyte membranes.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[(3-iodo
CAS Number
87862-25-7
Synonyms
- meta-Iodobenzylguanidine
- MIBG
Molecular Formula
C8H10IN3 • 1/2H2SO4
Formula Weight
324.1
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMSO: 2 mg/ml
- DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml
λmax
231 nm
SMILES
IC1=CC=CC(CNC(N)=N)=C1.O=S(O)(O)=O
InChi Code
InChI=1S/2C8H10IN3.H2O4S/c2*9-7-3-1-2-6(4-7)5-12-8(10)11;1-5(2,3)4/h2*1-4H,5H2,(H4,10,11,12);(H2,1,2,3,4)
InChi Key
XNACDNPGABUBFR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18015-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 18015-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1533426-72-0 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |