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Cayman Stigmasterol; Purity- Greater Than Or Equal To 95%; Size-
Product Description
NASPM is a synthetic analog of Joro spider toxin that blocks GluR2-lacking, Ca2+-permeable AMPA receptors. The blocking effect of NASPM on these receptors is use and voltage-dependent. At -60 mV, NASPM can suppress current responses in kainate-induced type II neurons (which are typified by strong inward rectification and high permeability to Ca2+) with an IC50 value of 0.33 µM. However, at +40 mV, NASPM does not affect Ca2+-permeable AMPA receptors. NASPM has been shown to protect against ischemia-induced neuronal cell death by preventing influx of toxic levels of Ca2+ into injured neurons. This compound can be used to study the role of GluR2 subunits in calcium permeability of AMPA receptors.,
WARNING This product is not for human or veterinary use.
Technical Information
- 1-Naphthylacetyl spermine
- DMSO: 1.7 mg/mL
- PBS (pH 7.2): 10 mg/mL
Shipping & Storage Information
| SKU | CAYM-18079-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 18079-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 83-48-7 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |