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Cayman Stigmasterol; Purity- Greater Than Or Equal To 95%; Size-
List Price
$249.00
Your Price
$249.00
Cayman Stigmasterol; Purity- Greater Than Or Equal To 95%; Size- 10 G; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18079-10
MFG.PART:
18079-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
ON-01910 is a potent, non-ATP-competitive inhibitor of polo-like kinase 1 (Plk1; IC50 = 9 nM), a serine/threonine protein kinase involved in the regulation of cell cycling. It induces apoptosis in a wide array of tumor cell lines (GI50 = 50-200 nM) and blocks the growth of multidrug resistant cancer cell lines.,,, ON-01910 is active in vivo when administered intraperitoneally and synergizes with chemotherapeutic agents, preventing tumor growth or abolishing tumors in human xenograft nude mouse models.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[2-
CAS Number
1225497-78-8
Synonyms
- Rigosertib
Molecular Formula
C21H25NO8S • Na
Formula Weight
473.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS (pH 7.2) (1:6): 0.14 mg/mL
- Ethanol: insolubloe
λmax
214, 241, 304 nm
SMILES
COC1=CC=C(CS(/C=C/C2=C(OC)C=C(OC)C=C2OC)(=O)=O)C=C1NCC([O-])=O.[Na+]
InChi Code
InChI=1S/C21H25NO8S.Na/c1-27-15-10-19(29-3)16(20(11-15)30-4)7-8-31(25,26)13-14-5-6-18(28-2)17(9-14)22-12-21(23)24;/h5-11,22H,12-13H2,1-4H3,(H,23,24);/q;+1/p-1/b8-7+;
InChi Key
VLQLUZFVFXYXQE-USRGLUTNSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18079-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 18079-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 83-48-7 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |