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Cayman Pd 153035; Purity- Greater Than Or Equal To 98%; Size- 25
List Price
$381.00
Your Price
$381.00
Cayman Pd 153035; Purity- Greater Than Or Equal To 98%; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18080-25
MFG.PART:
18080-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
PD 153035 is a potent, reversible inhibitor of EGFR kinase (Ki = 5.2 pM; IC50 = 29 pM).1 It less effectively inhibits HER2 (IC50 = 2.3 µM) and has little effect on several other receptor and non-receptor tyrosine kinases.1 PD 153035 has been shown to rapidly suppress autophosphorylation of EGFR in fibroblasts and human epidermoid carcinoma cells, as well as to selectively block EGF-mediated cellular processes, including mitogenesis and early gene expression.2,3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(3-
CAS Number
153436-54-5
Synonyms
- AG-1517
- NSC 669364
- SU 5271
Molecular Formula
C16H14BrN3O2
Formula Weight
360.2
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 0.3 mg/ml
- DMSO: 2 mg/ml
- DMSO:PBS (pH 7.2)(1:8): 0.11 mg/ml
- Ethanol: 0.2 mg/ml
λmax
222, 255, 346 nm
SMILES
COC(C(OC)=C1)=CC2=C1N=CN=C2NC3=CC(Br)=CC=C3
InChi Code
InChI=1S/C16H14BrN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)
InChi Key
LSPANGZZENHZNJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18080-25 |
|---|---|
| Featured | No |
| Supplier Part Number | 18080-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 153436-54-5 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |