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Cayman Lrrk2-In-1; Purity- Greater Than Or Equal To 95%; Size- 5
List Price
$112.00
Your Price
$112.00
Cayman Lrrk2-In-1; Purity- Greater Than Or Equal To 95%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18094-5
MFG.PART:
18094-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
AZD 1283 is an antagonist of the purinergic P2Y12 receptor (IC50 = 25 nM in a GTPγS assay in CHO cells). It selectively binds to the P2Y12 receptor (Kd = 11 nM) over more than 100 enzymes, receptors, and ion channels, including the P2Y1, platelet activating factor (PAF), and thromboxane A2 receptors, at 10 µM., AZD 1283 increases blood flow and inhibits platelet aggregation induced by ADP in a modified Folts dog model of thrombosis with ED50 values of 3 and 10 µg/kg per minute, respectively.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-cyano-2-
CAS Number
919351-41-0
Molecular Formula
C23H26N4O5S
Formula Weight
470.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMF:PBS (pH 7.2) (1:4): 0.20 mg/ml
- DMSO: 15 mg/ml
λmax
215, 296 nm
SMILES
CCOC(C1=CC(C#N)=C(N2CCC(C(NS(CC3=CC=CC=C3)(=O)=O)=O)CC2)N=C1C)=O
InChi Code
InChI=1S/C23H26N4O5S/c1-3-32-23(29)20-13-19(14-24)21(25-16(20)2)27-11-9-18(10-12-27)22(28)26-33(30,31)15-17-7-5-4-6-8-17/h4-8,13,18H,3,9-12,15H2,1-2H3,(H,26,28)
InChi Key
NEMHKCNXXRQYRF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18094-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 18094-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1234480-84-2 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |