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Cayman Ml167; Purity- Greater Than Or Equal To 98%; Size- 1 Mg
List Price
$26.00
Your Price
$26.00
Cayman Ml167; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18098-1
MFG.PART:
18098-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Antimycin A3 is a component of the antimycin A complex that is more polar than antimycin A1 (Item No. ) and antimycin A2 (Item No. ) but not antimycin A4 (Item No. ).,,, Antimycin A3 binds to the Q(inner) site of mitochondrial complex III (cytochrome bc1) and inhibits mitochondrial respiration (IC50 = 38 nM in isolated rat liver mitochondria). It also inhibits ATP-citrate lyase with a Ki value of 60.1 µM, and it stimulates the production of reactive oxygen species., In molecular modeling studies, antimycin binds to a mutant form of Bcl-2 (hBcl-2Δ22) and has a Kd value of 0.82 µM for binding to a recombinant mutant form of Bcl-2 (rhBcl-2Δ22) in an isothermal calorimetry assay.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2(or 3)-methyl-
CAS Number
522-70-3
Synonyms
- Blastomycin
- NSC 58239
Molecular Formula
C26H36N2O9
Formula Weight
520.6
Purity
≥98%
Formulation
A solid
Solubility
- DMF: Soluble
- DMSO: Soluble
- Ethanol: Soluble
- Methanol: Soluble
SMILES
CC(C)CC(O[C@@H]([C@@H]1C)[C@H](C(O[C@@H]([C@@H](C(O1)=O)NC(C(C=CC=C2NC([H])=O)=C2O)=O)C)=O)CCCC)=O
InChi Code
InChI=1S/C26H36N2O9/c1-6-7-9-18-23(37-20(30)12-14(2)3)16(5)36-26(34)21(15(4)35-25(18)33)28-24(32)17-10-8-11-19(22(17)31)27-13-29/h8,10-11,13-16,18,21,23,31H,6-7,9,12H2,1-5H3,(H,27,29)(H,28,32)/t15-,16+,18-,21+,23+/m1/s1
InChi Key
PVEVXUMVNWSNIG-PDPGNHKXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18098-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 18098-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1285702-20-6 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |