We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Cayman Elacridar; Purity- Greater Than Or Equal To 98%; Size- 1 M
List Price
$32.00
Your Price
$32.00
Cayman Elacridar; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18128-1
MFG.PART:
18128-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Elacridar is a dual inhibitor of P-glycoprotein (MRP-1, ABCB1) and breast cancer resistance protein (BCRP, ABCG2). It maximally inhibits P-glycoprotein in isolated human peripheral blood leukocytes at 200 nM. Elacridar blocks the activity of P-glycoprotein at the blood-brain barrier, altering the pharmacokinetics of certain drugs in the brain. This compound is effective against both human BCRP and the mouse homolog, Bcrp1.,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[4-[2-(3,4-dihydro-6,7-
CAS Number
143664-11-3
Synonyms
- GF120918
- GG918
- GW0918
Molecular Formula
C34H33N3O5
Formula Weight
563.6
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 5 mg/ml
- DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml
- DMSO: 1 mg/ml
λmax
258, 406 nm
SMILES
COC1=C(OC)C=C(CCN(CCC2=CC=C(NC(C3=CC=CC4=C3NC5=C(C=CC=C5OC)C4=O)=O)C=C2)C6)C6=C1
InChi Code
InChI=1S/C34H33N3O5/c1-40-28-9-5-7-26-32(28)36-31-25(33(26)38)6-4-8-27(31)34(39)35-24-12-10-21(11-13-24)14-16-37-17-15-22-18-29(41-2)30(42-3)19-23(22)20-37/h4-13,18-19H,14-17,20H2,1-3H3,(H,35,39)(H,36,38)
InChi Key
OSFCMRGOZNQUSW-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18128-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 18128-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United Kingdom |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 143664-11-3 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |