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Cayman Inosine-5-Monophosphate (Sodium Salt Hydrate); Purity- Gr
List Price
$32.00
Your Price
$32.00
Cayman Inosine-5-Monophosphate (Sodium Salt Hydrate); Purity- Greater Than Or Equal To 95%; Size- 5 G; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18135-5
MFG.PART:
18135-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
AP26113 is an orally bioavailable inhibitor of anaplastic lymphoma kinase (ALK; IC50 < 100 nM in Ba/F3 cells)., It is a pan-ALK inhibitor that also inhibits several ALK mutants that confer resistance to other ALK inhibitors, such as crizotinib (Item No. ), ceritinib (Item No. ), and CH5424802 (Item No. )., AP26113 blocks ALK activity and reduces growth in neuroblastoma cells, mouse xenograft, and Drosophila model systems harboring constitutively active ALK variants.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5- chloro- N4- [2- (dimethyl phosphinyl) phenyl]- N2- [2- methoxy-4- [4-(4- methyl-1- piperazinyl)- 1-piperidinyl] phenyl]- 2,4-pyrimidine diamine
CAS Number
1197953-54-0
Synonyms
- Brigatinib
Molecular Formula
C29H39ClN7O2P
Formula Weight
584.1
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 0.1 mg/ml
- Ethanol: 0.1 mg/ml
λmax
284 nm
SMILES
COC1=C(NC2=NC=C(Cl)C(NC3=CC=CC=C3P(C)(C)=O)=N2)C=CC(N4CCC(N5CCN(C)CC5)CC4)=C1
InChi Code
InChI=1S/C29H39ClN7O2P/c1-35-15-17-37(18-16-35)21-11-13-36(14-12-21)22-9-10-24(26(19-22)39-2)33-29-31-20-23(30)28(34-29)32-25-7-5-6-8-27(25)40(3,4)38/h5-10,19-21H,11-18H2,1-4H3,(H2,31,32,33,34)
InChi Key
AILRADAXUVEEIR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18135-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 18135-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 20813-76-7 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |