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Cayman 4-Acetoxy Det (Hydrochloride); Purity- Greater Than Or Equ
List Price
$70.00
Your Price
$70.00
Cayman 4-Acetoxy Det (Hydrochloride); Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18171-5
MFG.PART:
18171-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
ML-352 is a noncompetitive inhibitor of the presynaptic choline transporter (CHT) with Ki values of 92 and 166 nM for HEK293 cells expressing human CHT and mouse forebrain synaptosomes, respectively. It is selective for CHT over dopamine, norepinephrine, and serotonin transporters in HEK293 cells expressing human transporters when used at a concentration of 5 μM as well as a panel of 68 G protein-coupled receptors, ion channels, and transporters when used at a concentration of 10 μM. ML-352 (5 μM) increases cell surface expression of CHT without affecting total protein levels.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-methoxy-N- [[3-(1-methylethyl)- 5-isoxazolyl] methyl]-3- [(1-methyl-4- piperidinyl) oxy]-benzamide
CAS Number
1649450-12-3
Molecular Formula
C21H29N3O4
Formula Weight
387.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/ml
- DMSO: 20 mg/ml
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
- Ethanol: 5 mg/ml
λmax
212, 257 nm
SMILES
CN1CCC(OC2=C(OC)C=CC(C(NCC3=CC(C(C)C)=NO3)=O)=C2)CC1
InChi Code
InChI=1S/C21H29N3O4/c1-14(2)18-12-17(28-23-18)13-22-21(25)15-5-6-19(26-4)20(11-15)27-16-7-9-24(3)10-8-16/h5-6,11-12,14,16H,7-10,13H2,1-4H3,(H,22,25)
InChi Key
WBLVOWHFRUAMCP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18171-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 18171-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |