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Cayman (R)-Pramipexole (hydrochloride)
List Price
$556.00
Your Price
$556.00
Cayman (R)-Pramipexole (hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18234-50
MFG.PART:
18234-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Pramipexole (Item No. 11981) is an agonist of dopamine receptors that has applications in Parkinson’s disease and other disorders.1,2,3,4 Pramipexole is usually available as a mixture of enantiomers, with the majority of the dopamine receptor-dependent activity resulting from the (S) form.5 (R)-Pramipexole is an enantiomer of pramipexole that is ~100-fold less active than the (S) form as a dopamine receptor agonist.5,6 For this reason, it can be used as a negative control for the (S) form in the study of dopamine receptors. Both isoforms are antioxidants that target mitochondria to prevent apoptosis.5,7,8,9 This cytoprotective effect of (R)-pramipexole, without dopaminergic side effects, suggests utility in amyotrophic lateral sclerosis.5,10
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4,5,6,7-tetrahydro-N6-propyl-
CAS Number
104632-27-1
Synonyms
- Dexpramipexole
- KNS 760704
- (+)-Pramipexole
- SND 919CL2X
Molecular Formula
C10H17N3S • 2HCl
Formula Weight
284.2
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMSO: 5 mg/mL
- PBS (pH 7.2): 10 mg/mL
λmax
219, 264 nm
SMILES
CCCN[C@@H]1CCC(N=C(N)S2)=C2C1.Cl.Cl
InChi Code
InChI=1S/C10H17N3S.2ClH/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8;;/h7,12H,2-6H2,1H3,(H2,11,13);2*1H/t7-;;/m1../s1
InChi Key
QMNWXHSYPXQFSK-XCUBXKJBSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18234-50 |
|---|---|
| Supplier Part Number | 18234-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 104632-27-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |