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Cayman Diminutol; Purity- Greater Than Or Equal To 98%; Size- 5 M
List Price
$380.00
Your Price
$380.00
Cayman Diminutol; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18237-5
MFG.PART:
18237-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism that enables the synthesis of malonyl-CoA, a precursor for fatty acids. CP 640,186 is an isozyme-nonselective ACC inhibitor with IC50 values of 53 and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2, respectively. It has been shown to lower malonyl-CoA levels and to inhibit hepatic fatty acid and triglyceride synthesis both in vitro and in vivo. CP 640,186 can also stimulate muscle fatty acid oxidation (EC50 = 1.3 µM in rat epitrochlearis muscle strips) and lower whole body respiratory quotient in rats (ED50 = ~30 mg/kg).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
[(3R)-1-(9-anthracenylcarbonyl)[1,4-bipiperidin]-3-yl]-4-morpholinyl-methanone
CAS Number
591778-68-6
Molecular Formula
C30H35N3O3
Formula Weight
485.6
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
- PBS (pH 7.2): 10 mg/ml
SMILES
O=C([C@H]1CN(C2CCN(C(C3=C(C=CC=C4)C4=CC5=C3C=CC=C5)=O)CC2)CCC1)N6CCOCC6
InChi Code
InChI=1S/C30H35N3O3/c34-29(32-16-18-36-19-17-32)24-8-5-13-33(21-24)25-11-14-31(15-12-25)30(35)28-26-9-3-1-6-22(26)20-23-7-2-4-10-27(23)28/h1-4,6-7,9-10,20,24-25H,5,8,11-19,21H2/t24-/m1/s1
InChi Key
LDQKDRLEMKIYMC-XMMPIXPASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18237-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 18237-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 361431-33-6 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |