We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Cayman Temocapril (hydrochloride)
List Price
$128.00
Your Price
$128.00
Cayman Temocapril (hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18241-25
MFG.PART:
18241-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Temocapril is a prodrug form of the angiotensin-converting enzyme (ACE) inhibitor temocaprilat (Item No. 22169).1 Temocapril is converted to temocaprilat by carboxylesterase 1 (CES1).2 It prevents impairment of acetylcholine-induced relaxation in aortic rings isolated from diabetic rats in a model of streptozotocin-induced diabetes.3 Temocapril (0.1, 0.3, and 1 mg/kg) inhibits the angiotensin I-induced pressor response in normotensive rats.1 It prevents coronary vascular remodeling induced by L-NAME (Item No. 80210) in rats when administered at 0.1 mg/mL in the drinking water.4 Temocapril (1 mg/kg) reduces plasma glucose levels in a KKAy mouse model of type 2 diabetes.5
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
6-[[(1S)-1-(ethoxycarbonyl)3-
CAS Number
110221-44-8
Synonyms
- CS 622
Molecular Formula
C23H28N2O5S2 • HCl
Formula Weight
513.1
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 1 mg/mL
λmax
233 nm
SMILES
OC(CN1C([C@@H](N[C@@H](CCC2=CC=CC=C2)C(OCC)=O)CS[C@H](C3=CC=CS3)C1)=O)=O.Cl
InChi Code
InChI=1S/C23H28N2O5S2.ClH/c1-2-30-23(29)17(11-10-16-7-4-3-5-8-16)24-18-15-32-20(19-9-6-12-31-19)13-25(22(18)28)14-21(26)27;/h3-9,12,17-18,20,24H,2,10-11,13-15H2,1H3,(H,26,27);1H/t17-,18-,20-;/m0./s1
InChi Key
XDDQNOKKZKHBIX-ASBZXGSUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18241-25 |
|---|---|
| Supplier Part Number | 18241-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 110221-44-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |