We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Cayman Celecoxib-D7; Purity- Greater Than Or Equal To 99% Deutera
List Price
$826.00
Your Price
$826.00
Cayman Celecoxib-D7; Purity- Greater Than Or Equal To 99% Deuterated Forms (D1-D7); Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18248-5
MFG.PART:
18248-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Histone deacetylases (HDACs) catalyze the hydrolytic removal of acetyl groups from histone lysine residues, which commonly results in chromatin condensation and transcriptional repression., LMK 235 is an HDAC inhibitor that selectively targets HDACs 4 and 5 (IC50s = 12 and 4 nM, respectively) over other HDACs (IC50s = 56, 320, 850, 880, and 1,280 for HDACs 6, 1, 11, 2, and 8, respectively). It displays enhanced cytotoxic effects against human cancer cell lines, compared to SAHA (Item No. ) or trichostatin A (Item No. ). LMK 235 and derivatives inhibit the growth of the malarial parasite P. falciparum at multiple life cycle stages at nanomolar concentrations.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[[6-(hydroxyamino)-6-
CAS Number
1418033-25-6
Molecular Formula
C15H22N2O4
Formula Weight
294.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
- Ethanol: 10 mg/ml
SMILES
CC1=CC(C)=CC(C(NOCCCCCC(NO)=O)=O)=C1
InChi Code
InChI=1S/C15H22N2O4/c1-11-8-12(2)10-13(9-11)15(19)17-21-7-5-3-4-6-14(18)16-20/h8-10,20H,3-7H2,1-2H3,(H,16,18)(H,17,19)
InChi Key
VRYZCEONIWEUAV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18248-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 18248-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 544686-21-7 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |