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Cayman Donepezil-D4 (Hydrochloride); Purity- Greater Than Or Equa
List Price
$176.00
Your Price
$176.00
Cayman Donepezil-D4 (Hydrochloride); Purity- Greater Than Or Equal To 99% Deuterated Forms (D1-D4); Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18251-1
MFG.PART:
18251-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Isogarcinol is a natural polyisoprenylated benzophenone first isolated from plant species in the genus Garcinia. It has immunosuppressant actions, inhibiting the protein phosphatase calcineurin (IC50 = 36 µM) and suppressing the proliferation of T cells. Oral administration of isogarcinol in mice decreases delayed type hypersensitivity, prolongs graft survival in allogeneic skin transplants, suppresses inflammation in collagen-induced arthritis, and reduces clinical symptoms in experimental autoimmune encephalomyelitis.,, Isogarcinol inhibits the proliferation of HL-60 and PC-3 cancer cells (IC50s = 4 and 8 µg/ml, respectively) through cell cycle arrest and apoptosis.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3S,4aS,6R,8R )-10-(3,4-di hydroxybenzo yl)-3,4,5,6, 7,8-hexahydro -2,2,7,7-tet ramethyl-3,6, 8-tris(3-meth yl-2-buten-1- yl)-9H-4a,8- methano-2H-cy cloocta[b]py ran-9,11-di one
CAS Number
71117-97-0
Synonyms
- Cambogin
Molecular Formula
C38H50O6
Formula Weight
602.8
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/ml
- DMSO: 25 mg/ml
- DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml
- Ethanol: 20 mg/ml
λmax
228, 230, 276 nm
SMILES
CC([C@H](C/C=C(C)/C)C[C@]1(C[C@H](C/C=C(C)/C)C(C)(C)O2)C2=C3C(C4=CC(O)=C(O)C=C4)=O)(C)[C@](C/C=C(C)\C)(C1=O)C3=O
InChi Code
InChI=1S/C38H50O6/c1-22(2)11-14-26-20-37-21-27(15-12-23(3)4)36(9,10)44-33(37)30(31(41)25-13-16-28(39)29(40)19-25)32(42)38(34(37)43,35(26,7)8)18-17-24(5)6/h11-13,16-17,19,26-27,39-40H,14-15,18,20-21H2,1-10H3/t26-,27+,37+,38+/m1/s1
InChi Key
KXTNVBQRLRYVCO-LPSZMIQCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-18251-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 18251-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1219798-88-5 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |