Cayman (В±)-Nicotine-D3; Purity- Greater Than Or Equal To 99% Deu

(±)-Nicotine-d₃ is intended for use as an internal standard for the quantification of (±)-nicotine (Item No. 16535) by GC- or LC-MS. (±)-Nicotine is the racemic mixture of the dominant alkaloid found in tobacco plants. It acts as an agonist at neuronal nicotinic acetylcholine receptors (nAChRs; K_is = 481 and 11.1 nM for α3β4 and α4β2 subtypes, respectively) and possesses addictive and teratogenic properties.¹ (−)-(S)-Nicotine is significantly more active at binding nAChRs compared to the (+)-(R) antipode, thus nicotine is typically synthesized as (−)-(S)-nicotine with only 0.2-1% of the (+)-(R) isomer present.²

WARNING This product is not for human or veterinary use.