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Cayman Imatinib-D3; Purity- Greater Than Or Equal To 99% Deuterat
List Price
$101.00
Your Price
$101.00
Cayman Imatinib-D3; Purity- Greater Than Or Equal To 99% Deuterated Forms (D1-D3); Size- 500 Micrograms; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18257-500
MFG.PART:
18257-500
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
α-NAAG is a peptide neurotransmitter that is widely expressed throughout mammalian central and peripheral nervous systems. Following synaptic release, α-NAAG activates postsynaptic metabotropic glutamate receptor 3 (mGluR3) to inhibit cAMP production in neurons and astrocytes, as well as acts on presynaptic mGluR3 to inhibit the release of amine neurotransmitters, including GABA and glutamate., Increasing α-NAAG levels via NAAG peptidase inhibition reduces trauma-induced excitotoxic cell death in a mouse model of traumatic brain injury, as well as reduces hyperalgesia in various rodent pain models and schizophrenia-like stereotypic behaviors induced by phencyclidine in rats. Tumor levels of α-NAAG are positively correlated with tumor grade in patients with gliomas and meningiomas.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-acetyl-α-L-
CAS Number
3106-85-2
Synonyms
- NAAG
- N-Acetylaspartylglutamic Acid
- α-Spaglumic Acid
Molecular Formula
C11H16N2O8
Formula Weight
304.3
Purity
≥95%
Formulation
A solid
Solubility
- DMF: 20 mg/ml
- DMSO: 20 mg/ml
- Ethanol: 20 mg/ml
- PBS (pH 7.2): 10 mg/ml
SMILES
OC(CC[C@@H](C(O)=O)NC([C@@H](NC(C)=O)CC(O)=O)=O)=O
InChi Code
InChI=1S/C11H16N2O8/c1-5(14)12-7(4-9(17)18)10(19)13-6(11(20)21)2-3-8(15)16/h6-7H,2-4H2,1H3,(H,12,14)(H,13,19)(H,15,16)(H,17,18)(H,20,21)/t6-,7-/m0/s1
InChi Key
OPVPGKGADVGKTG-BQBZGAKWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18257-500 |
|---|---|
| Featured | No |
| Supplier Part Number | 18257-500 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1134803-18-1 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |