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Cayman (В±)-Naproxen-D3; Purity- Greater Than Or Equal To 99% Deu
List Price
$297.00
Your Price
$297.00
Cayman (В±)-Naproxen-D3; Purity- Greater Than Or Equal To 99% Deuterated Forms (D1-D3); Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18258-1
MFG.PART:
18258-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
GNE-477 is a dual inhibitor of PI3K (IC50 = 4 nM for PI3Kα) and mTOR (apparent Ki = 21 nM). It inhibits proliferation of MCF-7.1 cells with an EC50 value of 143 nM. It reduces tumor growth in a PC3-NCI tumor xenograft model when administered at doses ranging from 1 to 20 mg/kg per day.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-[7-methyl-
CAS Number
1032754-81-6
Molecular Formula
C21H28N8O3S2
Formula Weight
504.6
Purity
≥98%
Formulation
A solid
Solubility
- DMSO: soluble
SMILES
NC1=NC=C(C=N1)C2=NC(N3CCOCC3)=C(SC(CN4CCN(S(C)(=O)=O)CC4)=C5C)C5=N2
InChi Code
InChI=1S/C21H28N8O3S2/c1-14-16(13-27-3-5-29(6-4-27)34(2,30)31)33-18-17(14)25-19(15-11-23-21(22)24-12-15)26-20(18)28-7-9-32-10-8-28/h11-12H,3-10,13H2,1-2H3,(H2,22,23,24)
InChi Key
AKKCGLXULFRAET-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18258-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 18258-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 958293-77-1 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |