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Cayman (В±)-Naproxen-D3; Purity- Greater Than Or Equal To 99% Deu
List Price
$166.00
Your Price
$166.00
Cayman (В±)-Naproxen-D3; Purity- Greater Than Or Equal To 99% Deuterated Forms (D1-D3); Size- 500 Micrograms; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18258-500
MFG.PART:
18258-500
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Piperine is a natural alkaloid that can be isolated from black pepper. It activates transient receptor potential vanilloid type 1 receptor (TRPV1; EC50 = 38 µM) and modulates GABAA receptors (EC50s = 43-60 µM)., At similar levels, piperine inhibits both monoamine oxidases (MAOs), with IC50 values of 21 and 7 µM for MAO-A and MAO-B, respectively. Like other natural compounds containing methylenedioxyphenyl substituents, piperine affects cytochrome P450 (CYP) isoforms, inhibiting CYP3A species (Ki ~ 5 µM) and increasing expression of CYP1A and CYP2B in liver. It also has a biphasic effect on P-glycoprotein activity.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(2E,4E)-5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one
CAS Number
94-62-2
Synonyms
- Bioperine
- NSC 21727
- N-
Piperoylpiperidin
Molecular Formula
C17H19NO3
Formula Weight
285.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 10 mg/ml
- DMSO: 10 mg/ml
- DMSO:PBS (pH 7.2) (1:7): 0.1 mg/ml
- Ethanol: 10 mg/ml
λmax
255, 310, 345 nm
SMILES
O=C(/C=C/C=C/C1=CC(OCO2)=C2C=C1)N3CCCCC3
InChi Code
InChI=1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2/b6-2+,7-3+
InChi Key
MXXWOMGUGJBKIW-YPCIICBESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18258-500 |
|---|---|
| Featured | No |
| Supplier Part Number | 18258-500 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 958293-77-1 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |