Cayman Cardamonin; Purity- Greater Than Or Equal To 98%; Size- 10

Prostaglandin E₂ (PGE₂) activates four E prostanoid (EP) receptors, EP_1-4. EP₄ is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis.^,, L-902,688 is a highly potent agonist of the human PGE₂ receptor, EP₄. It demonstrates a K_i value of 0.38 nM and an EC₅₀ value of 0.6 nM and is >4,000-fold selective for EP₄ over other EP and prostanoid receptors. L-902,688 induces thermal hyperalgesia when injected into guinea pig forepaw and increases vasodilation of human pulmonary vein.^,

WARNING This product is not for human or veterinary use.