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Cayman MS049 (hydrochloride)
List Price
$49.00
Your Price
$49.00
Cayman MS049 (hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18348-1
MFG.PART:
18348-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
MS049 is a potent and selective inhibitor of PRMT4 (IC50 = 34 nM) and PRMT6 (IC50 = 43 nM). It is less active against additional type I PRMTs (IC50s = >130, >220, and 1.6 µM for PRMT1, PRMT3, and PRMT8, respectively) and displays no inhibition against type II or type III PRMTs nor any additional methyltransferases or nonepigenetic targets tested. MS049 has been shown to reduce the H3R2me2a mark in HEK293 cells with an IC50 value of 0.97 µM and also, unexpectedly, to reduce H4R3me2a in HEK293 cells. For more information on MS049 please visit the . The negative control, MS049N, for MS049 is also available exclusively through the SGC. You can submit a request to receive the negative control .
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-methyl-4-
CAS Number
2095432-59-8
Molecular Formula
C15H24N2O • 2HCl
Formula Weight
321.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 30 mg/mL
- PBS (pH 7.2): 10 mg/mL
SMILES
CNCCN(CC1)CCC1OCC2=CC=CC=C2.Cl.Cl
InChi Code
InChI=1S/C15H24N2O.2ClH/c1-16-9-12-17-10-7-15(8-11-17)18-13-14-5-3-2-4-6-14;;/h2-6,15-16H,7-13H2,1H3;2*1H
InChi Key
OPAWIOJQONUGQY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18348-1 |
|---|---|
| Supplier Part Number | 18348-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 2095432-59-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |