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Cayman L189; Purity- Greater Than Or Equal To 95%; Size- 50 Mg
List Price
$546.00
Your Price
$546.00
Cayman L189; Purity- Greater Than Or Equal To 95%; Size- 50 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18374-50
MFG.PART:
18374-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
L189 is a competitive inhibitor of DNA ligases I, III, and IV (IC50s = 5, 9, and 5 µM, respectively).1 It blocks DNA binding (Ki = 5 µM for DNA ligase I), increasing the cytotoxicity of DNA-damaging agents, including ionizing radiation.1 L189 preferentially inhibits the interaction of the ligase with damaged DNA, inhibiting base excision repair and non-homologous end-joining.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
6-amino-
CAS Number
64232-83-3
Molecular Formula
C11H10N4OS
Formula Weight
246.3
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 20 mg/ml
- DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 0.3 mg/ml
λmax
222, 294, 360, 378 nm
SMILES
NC(N1)=C(/N=C/C2=CC=CC=C2)C(NC1=S)=O
InChi Code
InChI=1S/C11H10N4OS/c12-9-8(10(16)15-11(17)14-9)13-6-7-4-2-1-3-5-7/h1-6H,(H4,12,14,15,16,17)/b13-6+
InChi Key
SAKOXVNKDMWWLF-AWNIVKPZSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18374-50 |
|---|---|
| Featured | No |
| Supplier Part Number | 18374-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 64232-83-3 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |