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Cayman Vidofludimus; Purity- Greater Than Or Equal To 98%; Size-
List Price
$485.00
Your Price
$485.00
Cayman Vidofludimus; Purity- Greater Than Or Equal To 98%; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18377-25
MFG.PART:
18377-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Dihydroorotate dehydrogenase (DHODH) is involved in pyrimidine nucleoside biosynthesis. DHODH inhibitors have value in autoimmune diseases as well as cancer and certain infections.1 Vidofludimus is an immunosuppressive drug that inhibits DHODH (IC50s = 0.134, 1.29, and 10.6 µM for human, rat, and mouse isoforms, respectively).2,3 Through this action, it inhibits the proliferation of T cells and B cells and the secretion of IL-17 (IC50s = 12.9, 3.7, and 6.0 µM, respectively, in human cells).2,3 Oral administration of vidofludimus improves both chronic dextran sodium sulfate-
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[[(3-fluoro-3-
CAS Number
717824-30-1
Synonyms
- 4SC-101
Molecular Formula
C20H18FNO4
Formula Weight
355.4
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 25 mg/ml
- DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml
- DMSO: 25 mg/ml
λmax
261, 293 nm
SMILES
COC1=CC(C2=CC(F)=C(NC(C3=C(C(O)=O)CCC3)=O)C=C2)=CC=C1
InChi Code
InChI=1S/C20H18FNO4/c1-26-14-5-2-4-12(10-14)13-8-9-18(17(21)11-13)22-19(23)15-6-3-7-16(15)20(24)25/h2,4-5,8-11H,3,6-7H2,1H3,(H,22,23)(H,24,25)
InChi Key
XPRDUGXOWVXZLL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18377-25 |
|---|---|
| Featured | No |
| Supplier Part Number | 18377-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 717824-30-1 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |