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Cayman NVP-ADW742
List Price $40.00 Your Price $40.00
Cayman NVP-ADW742 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-18390-1
MFG.PART: 18390-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
NVP-ADW742 is an insulin-like growth factor 1 receptor (IGF-1R) inhibitor with an IC50 value of 0.17 µM. It exhibits 6-fold greater selectivity for IGF-1R over the insulin receptor (InsR) kinase and minimal inhibitory activity against c-Kit, HER1, PDGFR, VEGFR2, or Bcr-Abl p210. NVP-ADW742 has been shown to inhibit tumor proliferation both in vitro and in a mouse model of multiple myeloma.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-[3-
CAS Number
475488-23-4
Synonyms
- ADW742
- GSK552602A
Molecular Formula
C28H31N5O
Formula Weight
453.6
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 30 mg/mL
- Ethanol:PBS (pH 7.2) (1:10): 0.09 mg/mL
λmax
288 nm
SMILES
NC1=NC=NC2=C1C(C3=CC=CC(OCC4=CC=CC=C4)=C3)=CN2[C@@H]5C[C@@H](CN6CCCC6)C5
InChi Code
InChI=1S/C28H31N5O/c29-27-26-25(22-9-6-10-24(15-22)34-18-20-7-2-1-3-8-20)17-33(28(26)31-19-30-27)23-13-21(14-23)16-32-11-4-5-12-32/h1-3,6-10,15,17,19,21,23H,4-5,11-14,16,18H2,(H2,29,30,31)/t21-,23-
InChi Key
LSFLAQVDISHMNB-AFARHQOCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18390-1 |
|---|---|
| Supplier Part Number | 18390-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 475488-23-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |