We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Cayman FLT3 Inhibitor
List Price
$525.00
Your Price
$525.00
Cayman FLT3 Inhibitor - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18462-50
MFG.PART:
18462-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Fms-like tyrosine kinase (FLT3) is a cell-surface receptor with important roles in stem cell development, hematopoiesis, and cancer.1,2 FLT3 Inhibitor is a cell-permeable, ATP-competitive inhibitor of FLT3 (IC50 = 27 nM) that blocks the proliferation of myelomonocytic leukemia MV4-11 cells (IC50 = 0.41 µM).3 It is selective for FLT3 over a panel of 22 other kinases. FLT3 Inhibitor synergistically increases the cytotoxicity of an AF4-mimetic peptide against MV4-11 cells.4
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[(3,4-
CAS Number
301305-73-7
Synonyms
- Fms-like Tyrosine Kinase Inhibitor
- TCS 359
Molecular Formula
C18H20N2O4S
Formula Weight
360.4
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 5 mg/mL
- DMF:PBS (pH 7.2)(1:3): 0.25 mg/mL
- DMSO: 3 mg/mL
λmax
220, 256, 349 nm
SMILES
COC1=C(OC)C=CC(C(NC2=C(C(N)=O)C3=C(CCCC3)S2)=O)=C1
InChi Code
InChI=1S/C18H20N2O4S/c1-23-12-8-7-10(9-13(12)24-2)17(22)20-18-15(16(19)21)11-5-3-4-6-14(11)25-18/h7-9H,3-6H2,1-2H3,(H2,19,21)(H,20,22)
InChi Key
FSPQCTGGIANIJZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18462-50 |
|---|---|
| Supplier Part Number | 18462-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 301305-73-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |