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Cayman ABT-333
List Price
$190.00
Your Price
$190.00
Cayman ABT-333 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18482-25
MFG.PART:
18482-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
ABT-333 is an inhibitor of hepatitis C virus (HCV) RNA-dependent RNA polymerase (RdRp; IC50s = 0.0022-0.0107 µM for genotypes 1a and 1b).1 It is selective for HCV genotype 1 polymerases over genotypes 2, 3, and 4 (IC50s = 0.9->20 µM), as well as human polymerases (IC50s = >100 µM). Formulations containning ABT-333, ombitasvir, paritaprevir, and ritonavir have been used in the treatment of HCV genotype 1 infections.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[6-[5-(3,4- dihydro-2,4- dioxo-1(2H)- pyrimidinyl)-3- (1,1-dimethylethyl)- 2-methoxyphenyl]- 2-naphthalenyl]- methanesulfonamide
CAS Number
1132935-63-7
Synonyms
- Dasabuvir
Molecular Formula
C26H27N3O5S
Formula Weight
493.5
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMF: 30 mg/mL
- DMF:PBS (pH 7.2)(1:3): 0.25 mg/mL
- DMF:PBS (pH 7.2)(1:3): 0.25 mg/mL
- DMSO: 20 mg/mL
- DMSO: 20 mg/mL
λmax
244 nm
SMILES
CC(C)(C)C1=C(OC)C(C2=CC3=CC=C(NS(C)(=O)=O)C=C3C=C2)=CC(N4C=CC(NC4=O)=O)=C1
InChi Code
InChI=1S/C26H27N3O5S/c1-26(2,3)22-15-20(29-11-10-23(30)27-25(29)31)14-21(24(22)34-4)18-7-6-17-13-19(28-35(5,32)33)9-8-16(17)12-18/h6-15,28H,1-5H3,(H,27,30,31)
InChi Key
NBRBXGKOEOGLOI-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18482-25 |
|---|---|
| Supplier Part Number | 18482-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1132935-63-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |