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Cayman ME0328
List Price $253.00 Your Price $253.00
Cayman ME0328 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-18488-25
MFG.PART: 18488-25
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
The poly(ADP-ribose) polymerases (PARPs) are enzymes with roles in DNA repair, apoptosis, inflammation, and other cellular events, particularly in response to reactive oxygen and nitrogen species.1,2 ME0328 is an inhibitor of PARP3 (IC50 = 0.89 µM), which is a regulator of DNA repair and mitotic progression.3 It displays selectivity for PARP3 over 12 other PARP family members. ME0328 is cell permeable and elicits PARP3-specific effects at submicromolar concentrations.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3,4-dihydro-
CAS Number
1445251-22-8
Molecular Formula
C19H19N3O2
Formula Weight
321.4
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 12 mg/mL
- DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL
- DMSO: 17 mg/mL
- Ethanol: 0.2 mg/mL
λmax
224, 263 nm
SMILES
O=C1C2=CC=CC=C2NC(CCC(N[C@@H](C)C3=CC=CC=C3)=O)=N1
InChi Code
InChI=1S/C19H19N3O2/c1-13(14-7-3-2-4-8-14)20-18(23)12-11-17-21-16-10-6-5-9-15(16)19(24)22-17/h2-10,13H,11-12H2,1H3,(H,20,23)(H,21,22,24)/t13-/m0/s1
InChi Key
QIHBWVVVRYYYRO-ZDUSSCGKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18488-25 |
|---|---|
| Supplier Part Number | 18488-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1445251-22-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |