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Cayman Cdk1/5 Inhibitor
List Price $54.00 Your Price $54.00
Cayman Cdk1/5 Inhibitor - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-18740-1
MFG.PART: 18740-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Cyclin-dependent kinases (Cdks) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. Cdk1/5 Inhibitor is a pyrazolo [3,4-b] quioxaline that inhibits Cdk1/cyclin B and Cdk5/p25 (IC50s = 600 and 400 nM, respectively). It less potently inhibits GSK3β (IC50 = 1 µM) and does not block Cdc25 activity. This compound is used to help define the roles of Cdk1 and Cdk5 in various signaling pathways.,,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1H-pyrazolo[3,4-b]quinoxalin-
CAS Number
40254-90-8
Synonyms
- Cyclin-dependent kinase 1/5 Inhibitor
- NSC 693868
Molecular Formula
C9H7N5
Formula Weight
185.2
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 3 mg/mL
- DMSO: 5 mg/mL
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL
λmax
254, 334 nm
SMILES
NC1=NNC2=NC3=C(N=C21)C=CC=C3
InChi Code
InChI=1S/C9H7N5/c10-8-7-9(14-13-8)12-6-4-2-1-3-5(6)11-7/h1-4H,(H3,10,12,13,14)
InChi Key
DWHVZCLBMTZRQM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18740-1 |
|---|---|
| Supplier Part Number | 18740-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 40254-90-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |