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Cayman Bifonazole
List Price $354.00 Your Price $354.00
Cayman Bifonazole - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-18744-25
MFG.PART: 18744-25
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Bifonazole is a topically-active imidazole antifungal compound that has broad spectrum activity in vitro against dermatophytes, molds, yeasts, dimorphic fungi, and some Gram-positive bacteria.1,2 It is effective in the treatment of experimental dermatophytic and Candida in animals.2 Bifonazole is also a potent inhibitor of cytochrome P450 aromatase (Ki = 68 nM, IC50 = 270 nM), which catalyzes the biosynthesis of estrogens from androgens.3 When applied topically in animals, it demonstrates prolonged retention time in skin with minimal percutaneous absorption, thus minimizing its effect on aromatase.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-([1,1-biphenyl]-4-
CAS Number
60628-96-8
Synonyms
- BAY-H 4502
- (±)-Bifonazole
Molecular Formula
C22H18N2
Formula Weight
310.4
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 25 mg/mL
- DMF:PBS (pH 7.2) (1:4): 0.2 mg/mL
- DMSO: 16 mg/mL
- Ethanol: 10 mg/mL
λmax
254 nm
SMILES
C1(C(N2C=NC=C2)C3=CC=C(C4=CC=CC=C4)C=C3)=CC=CC=C1
InChi Code
InChI=1S/C22H18N2/c1-3-7-18(8-4-1)19-11-13-21(14-12-19)22(24-16-15-23-17-24)20-9-5-2-6-10-20/h1-17,22H
InChi Key
OCAPBUJLXMYKEJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18744-25 |
|---|---|
| Supplier Part Number | 18744-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 60628-96-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |