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Cayman Ivermectin B1a
List Price
$624.00
Your Price
$624.00
Cayman Ivermectin B1a - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18768-25
MFG.PART:
18768-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Ivermectin B1a is the main component (>80%) of the anthelmintic ivermectin, which also contains ivermectin B1b (<20%; Item No. ). It produces antiparasitic activity by binding to glutamate-gated chloride channels expressed on nematode neurons and pharyngeal muscle cells, inducing irreversible channel opening and very long-lasting hyperpolarization/depolarization of the neuron/muscle cell, thereby blocking further function (EC50 = 104 nM)., Formulations containing ivermectin inhibit replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Vero/hSLAM cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-O-demethyl-
CAS Number
71827-03-7
Synonyms
- 22,23-dihydro Avermectin B1a
Molecular Formula
C48H74O14
Formula Weight
875.1
Purity
≥95%
Formulation
A solid
Solubility
- DMSO: soluble
SMILES
C/C([C@@H](O[C@@]1([H])C[C@H](OC)[C@@H](O[C@]2([H])O[C@@H](C)[C@H](O)[C@@H](OC)C2)[C@H](C)O1)[C@@H](C)/C=C/C=C(CO3)/[C@@]([C@@]3([H])[C@H](O)C(C)=C4)(O)[C@]4([H])C5=O)=C\C[C@]6([H])C[C@@](O5)([H])C[C@]7(CC[C@H](C)[C@]([C@H](CC)C)([H])O7)O6
InChi Code
InChI=1S/C48H74O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,19,25-26,28,30-31,33-45,4
InChi Key
AZSNMRSAGSSBNP-XPNPUAGNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18768-25 |
|---|---|
| Supplier Part Number | 18768-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Australia |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 71827-03-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |