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Cayman MitoPBN
List Price
$464.00
Your Price
$464.00
Cayman MitoPBN - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18809-10
MFG.PART:
18809-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
MitoPBN is a mitochondria-targeted antioxidant. It accumulates in the mitochondria following the generation of a mitochondrial membrane potential by succinate, an effect that is blocked by addition of the mitochondrial membrane potential uncoupler FCCP (Item No. ). MitoPBN inhibits superoxide activation of mitochondrial uncoupling protein 1 (UCP1), UCP2, and UCP3 when used at a concentration of 250 nM in vitro but does not react with superoxide. It traps hydroxyl (IC50 = ~77 µM) and carbon-centered radicals and inhibits the initiation of lipid peroxidation in isolated bovine heart mitochondria.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
[4-[4-[[(1,1-
CAS Number
652968-37-1
Molecular Formula
C33H37NO2P • Br
Formula Weight
590.5
Purity
≥95%
Formulation
A solid
Solubility
- DMF: 25 mg/mL
- DMF:PBS(pH7.2) (1:2): 0.33 mg/mL
- DMSO: 1 mg/mL
- Ethanol: 0.33 mg/mL
λmax
303, 406, 659 nm
SMILES
CC(C)(C)/[N+]([O-])=C/C(C=C1)=CC=C1OCCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.[Br-]
InChi Code
InChI=1S/C33H37NO2P.BrH/c1-33(2,3)34(35)27-28-21-23-29(24-22-28)36-25-13-14-26-37(30-15-7-4-8-16-30,31-17-9-5-10-18-31)32-19-11-6-12-20-32;/h4-12,15-24,27H,13-14,25-26H2,1-3H3;1H/q+1;/p-1/b34-27-;
InChi Key
JZMWLDMVLIVXEF-KWYZZNRTSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18809-10 |
|---|---|
| Supplier Part Number | 18809-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 652968-37-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |