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Cayman N6-benzoyl-Cyclic AMP (sodium salt)
List Price $498.00 Your Price $498.00
Cayman N6-benzoyl-Cyclic AMP (sodium salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-18819-10
MFG.PART: 18819-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
N6-benzoyl-Cyclic AMP (6-Bnz-cAMP) is a cell permeable cAMP analog that selectively activates PKA over exchange proteins activated by cAMP (Epac1 and 2, also known as RAPGEF3 and 4). It binds the AI and AII subunits of PKA with pKi values of 4.0 and 3.8, respectively, whereas it binds Epac1 with a pKi value of 1.3. 6-Bnz-cAMP stimulates the phosphorylation of the PKA substrate CREB but does not activate the Epac target Rap1. It can act synergistically with Epac-selective activators, such as 8-pCPT-2’-O-Me-cAMP (Item No. ).,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-benzoyl-
CAS Number
1135306-29-4
Synonyms
- 6-Bnz-cAMP
Molecular Formula
C17H15N5O7P • Na
Formula Weight
455.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- PBS (pH 7.2): 3 mg/mL
λmax
282 nm
SMILES
O[C@H]1[C@H](N2C=NC3=C2N=CN=C3NC(C4=CC=CC=C4)=O)O[C@@]5([H])[C@@]1([H])OP(OC5)([O-])=O.[Na+]
InChi Code
InChI=1S/C17H16N5O7P.Na/c23-12-13-10(6-27-30(25,26)29-13)28-17(12)22-8-20-11-14(18-7-19-15(11)22)21-16(24)9-4-2-1-3-5-9;/h1-5,7-8,10,12-13,17,23H,6H2,(H,25,26)(H,18,19,21,24);/q;+1/p-1/t10-,12-,13-,17-;/m1./s1
InChi Key
SPYGSKQRPXISIB-FKVBDRBCSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18819-10 |
|---|---|
| Supplier Part Number | 18819-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Germany |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1135306-29-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |